Gene description for PAICS
Gene name	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
Gene symbol	PAICS
Other names/aliases	ADE2 ADE2H1 AIRC PAICSD PAIS
Species	Homo sapiens
Experiment description of studies that identified PAICS in Chronic lymphocytic leukemia cells
1 Experiment ID 901 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 26100252    Organism Homo sapiens Experiment description Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Authors Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. Journal name Blood Publication year 2015 Sample Chronic lymphocytic leukemia cells Sample name JVM-3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.15-1.17 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV150015: EV-METRIC:22%, 44%
2 Experiment ID 902 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 26100252    Organism Homo sapiens Experiment description Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Authors Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. Journal name Blood Publication year 2015 Sample Chronic lymphocytic leukemia cells Sample name MEC-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.15-1.17 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry FACS Western blotting EV-TRACK EV150015: EV-METRIC:22%, 44%